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Extropy Institute
Probably the largest Transhumanist organization. EI advocates using technology to extend healthy life, augment intelligence, optimize psychology, and improve social systems.
http://www.extropy.org/
Plausible Futures
List of sites for future scenarios and planning in various fields from economics and management to technology. Includes a newsletter.
http://www.plausiblefutures.com/
The Life Extension Foundation
Sells supplements and funds/reports on research in life extension and methods to slow and reverse human aging.
http://www.lef.org
Transhumanist Art Centre
The website for the Extropic Art Movement, 'insight into the future directions of art and creativity.' Managed by artist Natasha Vita-More.
http://www.extropic-art.com/
